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Reagent for Semi Auto Biochemistry -Aspen ALT

The in vitro quantitative determination of ALT (SGPT) in human serum or plasma is a crucial diagnostic test used to assess liver function. The performance characteristics of this test ensure accuracy and reliability. The measuring range is designed to determine ALT activities corresponding to a maximum absorbance change per minute (ΔA/min) of 0.16 at 340 and 334 nm, or 0.08 at 365 nm. For samples exceeding these values, a 1 + 9 dilution with NaCl solution (9 g/l) is recommended, and results should be multiplied by 10.

Specificity and interference studies reveal no interference from ascorbic acid up to 40 mg/dl, bilirubin up to 40 mg/dl, glucose up to 500 mg/dl, and lipemia up to 2,000 mg/dl triglycerides. The test's sensitivity is robust, with a lower limit of detection at 4 U/l. At 37°C, the test demonstrates excellent precision, making it a reliable tool for clinical assessments of liver health.

Features:

     

    • Wide Measuring Range: Capable of accurately determining ALT activities with a maximal absorbance change per minute (ΔA/min) of 0.16 at 340 and 334 nm, or 0.08 at 365 nm, ensuring comprehensive measurement capabilities.

    • High Specificity: Exhibits no interference from common substances such as ascorbic acid up to 40 mg/dl, bilirubin up to 40 mg/dl, glucose up to 500 mg/dl, and lipemia up to 2,000 mg/dl triglycerides, ensuring reliable and specific results.

    • Excellent Sensitivity: Features a lower limit of detection at 4 U/l, allowing for the detection of even minimal ALT levels, crucial for early diagnosis and monitoring of liver function.

    • Precision and Accuracy: Delivers precise and consistent results at 37°C, making it a dependable tool for clinical laboratories to assess and monitor liver health with confidence.